Which disease shows features such as developmental delays and heart defects at birth?

Which disease shows features such as developmental delays and heart defects at birth?

• A. Duchenne Muscular Dystrophy
• B. Cystic Fibrosis
• C. Down's Syndrome
• D. Huntington's Disease

Answer: (C)

Down's Syndrome, also known as Trisomy 21, is characterized by a range of features that may include developmental delays and congenital heart defects. Children with Down's Syndrome often experience varying degrees of intellectual disability and may have physical characteristics such as a flat facial profile, slanted eyes, and a single transverse palmar crease. Heart defects are particularly common in individuals with this condition, notably atrioventricular septal defects and other congenital heart issues, which can lead to serious health complications. In contrast, the other options do not primarily present with these specific features. Duchenne Muscular Dystrophy is primarily a muscle-degenerative disease with no direct link to developmental delays at birth. Cystic Fibrosis mostly affects the lungs and digestive system but does not typically involve heart defects or developmental delays as initial presenting features. Huntington's Disease is a neurodegenerative disorder that typically manifests in adulthood with movement disorders and cognitive decline, rather than presenting developmental delays at birth. Therefore, Down's Syndrome is the most accurate choice among the provided options.

Down's Syndrome, also known as Trisomy 21, is characterized by a range of features that may include developmental delays and congenital heart defects. Children with Down's Syndrome often experience varying degrees of intellectual disability and may have physical characteristics such as a flat facial profile, slanted eyes, and a single transverse palmar crease. Heart defects are particularly common in individuals with this condition, notably atrioventricular septal defects and other congenital heart issues, which can lead to serious health complications.

In contrast, the other options do not primarily present with these specific features. Duchenne Muscular Dystrophy is primarily a muscle-degenerative disease with no direct link to developmental delays at birth. Cystic Fibrosis mostly affects the lungs and digestive system but does not typically involve heart defects or developmental delays as initial presenting features. Huntington's Disease is a neurodegenerative disorder that typically manifests in adulthood with movement disorders and cognitive decline, rather than presenting developmental delays at birth. Therefore, Down's Syndrome is the most accurate choice among the provided options.